The Tangled History of mRNA Vaccines

The Tangled History of mRNA Vaccines Hundreds of scientists had worked on mRNA vaccines for decades before the coronavirus pandemic brought a breakthrough. In late 1987, Robert Malone performed a landmark experiment. He mixed strands of messenger RNA with droplets of fat, to create a kind of molecular stew. Human cells bathed in this genetic…

Quest to use CRISPR against disease gains ground

Quest to use CRISPR against disease gains ground   As the first clinical-trial results trickle in, researchers look ahead to more sophisticated medical applications for genome editing. Heidi Ledford   The prospect of using the popular genome-editing tool CRISPR to treat a host of diseases in people is moving closer to reality. Medical applications of…